Genetic profile of the bvl lutra lutra population study

Sun Visal, Mahood, S.

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Roberton, S. Factors affecting success of PCR amplification of microsatellite loci from otter faeces. In conclusion, somatic mutation profiling using archival FFPE samples from gallbladder cancer is feasible. Nature Reviews. All cases were formalin-fixed and paraffin-embedded FFPE.

Genetic profile of the bvl lutra lutra population study

An impetus for such characterization is the potential of targeted therapies directed against the products of these molecular aberrations including the tumor proteomic profile. Plasma collection and cfDNA isolation Whole blood was collected in ethylenediaminetetraacetic acid—containing tubes and centrifuged and spun twice within 2 hours to yield plasma. We thank Phien Sayon and Nay Sonsak for producing the map. Fourteen hotspot mutations Table 2 were identified from eleven different tumors within this sample set, with three cases demonstrating more than 1 mutation. Sun Visal, Mahood, S. Duckworth, J. Eurasian otter trails and scats are frequently found in the routes along the riverside, where the samples had been collected. Therefore, novel ultrasensitive technologies capable of testing for a broad spectrum of molecular alterations are needed to further personalized cancer therapy. Enrichment of target sequences exons of cancer-related genes and 37 introns from 14 genes recurrently rearranged in cancer representing approximately 1. Genetic diversity in the Eurasian, 73— The results were retrospectively compared to molecular testing of archival primary or metastatic tumor tissue obtained at different points of clinical care. On NGS, 26 mutations were noted in 15 cases. In conclusion, somatic mutation profiling using archival FFPE samples from gallbladder cancer is feasible. Escaping from the populated urban territory important communities of birds and mammals have found in the BVL a safe refuge, as the otter.

Foster-Turley, S. In: IUCN Approval for the study was obtained from the institutional review board at MD Anderson Cancer Center.

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Molecular Characterization of Gallbladder Cancer using Somatic Mutation Profiling